Urinary Prognostic Biomarkers in Patients With Focal Segmental Glomerulosclerosis

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urinary prognostic biomarkers in patients with focal segmental glomerulosclerosis

background: focal segmental glomerulosclerosis (fsgs) is a type of nephrotic syndrome which is diagnosed by renal biopsy. degree of the proteinuria, renal dysfunction, histologic findings and the response to therapy are some factors used for evaluating the prognosis of fsgs. objectives: in the present study, we attempted to discover some protein candidates for disease prognosis related to glome...

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Urinary Prognostic Biomarkers in Patients With Focal Segmental Glomerulosclerosis

BACKGROUND Focal segmental glomerulosclerosis (FSGS) is a type of nephrotic syndrome which is diagnosed by renal biopsy. Degree of the proteinuria, renal dysfunction, histologic findings and the response to therapy are some factors used for evaluating the prognosis of FSGS. OBJECTIVES In the present study, we attempted to discover some protein candidates for disease prognosis related to glome...

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Urinary proteome and potential biomarkers associated with serial pathogenesis steps of focal segmental glomerulosclerosis.

BACKGROUND Focal segmental glomerulosclerosis (FSGS) is a chronic nephropathy showing characteristic glomerular sclerosis. So far, the diagnosis and prognosis of FSGS rely mainly on the invasive biopsy. Searching for potential FSGS-associated urinary biomarkers representing pre-sclerotic and serial sclerotic stages of FSGS could be helpful to the non-invasive diagnosis and prognosis of FSGS. ...

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Focal Segmental Glomerulosclerosis.

Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant-important disease characteristics. In contrast, adaptive FSGS is associated with excessive nephron workload due to increased body size, reduced nephron ...

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Idiopathic focal segmental glomerulosclerosis.

Idiopathic focal segmental glomerulosclerosis (FSGS) is a primary glomerular disease that essentially represents a form of chronic, progressive renal fibrosis for which there is no discernible cause. Often presenting with or eventually manifesting the nephrotic syndrome, this disease is increasing in incidence in both children and adults. Therapy continues to be a challenge, although some patie...

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ژورنال

عنوان ژورنال: Nephro-Urology Monthly

سال: 2014

ISSN: 2251-7006,2251-7014

DOI: 10.5812/numonthly.16806